This study was conducted to assess the determinants of adoption of agricultural technologies introduced by MARKETS II project to small-holder farmers in Southwest, Nigeria. Specifically, the study assessed the level of adoption of USAID MARKETS II project’s technologies and the also the factors determining the adoption of these technologies. Multistage sampling procedure was used to select a sample size of 525 farmers, out of which 254 were project participants and 271 were non- participants of the project. Questionnaires were used to collect the data from the respondents. The results were analysed using frequencies and percentages and Binary Logit regression. The results revealed that factors that determined the adoption of technologies introduced by MARKETS II project included educational status, farm size, farming experience, membership in cooperative societies, annual income and number of extension visits. However, farming experience had a negative relationship. Also, the agricultural technologies introduced by MARKETS II project were well adopted by the farmers as all the mean values (3.0833 to 4.6909) were greater than the weighted mean (3). The study therefore recommends that smallholder farmers should be encouraged to join cooperative societies as this was shown to boost their exposure to new technology and special educational facilities should also be provided for the farmers for them to achieve a higher level of education as this has implications for technology adoption.