Background: Economic development alters the natural environment and sometimes harms ecosystems in terms of the humanly useful services they provide, their diversity, and their resilience. We are coming to understand that all of this has significant consequences for human health. Environmental health has been understood as a public health issue in relation to air quality, water quality, and exposure to environmental pollutants that are toxic, carcinogenic, or teratogenic or are chemically bioactive in other ways. Aim: This study investigates the effect of inhaling cement particles on some coagulation profiles among the brick layers and block makers in Owo, Ondo State. Method: This was cross-sectional descriptive and analysis of 50 brick layers and block makers together with 50 non brick layers nor block makers that serve as controls. Results: The results from the study shows a statistically significant increase in platelet count (p<0.05) when compared to the control, while a statistically significant reduced time of PT and APTT were recorded (p<0.05). The is no statistically significant results when the years of exposure were considered as shown in table 2 (p>0.05)Conclusion: The results of this work shows that exposure to cement particles exposes the workers to hypercoagulability which is a tendency to thrombosis and thromboembolism and can also leads to cardiovascular disease.