2020-06-27T00:00:00Background: Healthcare workers (HCWs) form a significant risk group for infection of Corona virus. Objectives: The aim of this survey was to assess the knowledge, attitude and behavior of HCWs in the State Specialist Hospital Gombe on coronavirus. Methods: 44 HCWs from different department in the State Specialist Hospital Gombe were randomly invited to fill a questionnaire developed to cover the survey objectives from 23rd March to 6th April 2020. The response rate was 100%. Descriptive statistics was used to summarize the responses. Results: A total of 38.6% were Medical Laboratory Scientist, 36.6% were Nurses and 9.09% were Pharmacists. The most common sources of Coronavirus (COVID-19) information were the Main stream Media (TV) which have 20.5% and 18.2% of Social media (Facebook, WhatsApp etc.). Only 59.1% of HCWs are aware of the Infection Prevention and Control program in the Hospital. About 97.7% agreed that HCWs are at greater risks of been infected by the novel corona virus. 95.5% of HCWs reported that they are worried that one of their family members may get infected. Conclusions: The knowledge about emerging infectious diseases was poor and there is need for further education and re-training programs particularly in the use of personal protective equipment, the operations of the quarantine and isolation unit and infection control measures. The self-reported infection control practices were sub-optimal and seem to be overestimated.