Greener Journal of Medical Sciences

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Muhammad et al

Greener Journal of  Medical Sciences Vol. 7 (3), pp. 032-035, June 2017.

 ISSN: 2276-7797  

Research Paper

Manuscript Number: 052117065



Deficiency of Serum Alphatocopherol among Oral Hormonal Based Contraceptives Users in Sokoto Metropolis, Nigeria


*1Muhammad Y, 2Kani YA, 3Umar FA and 4Zainab I


1Department of Chemical Pathology, School of Medical Laboratory Science, Usmanu Danfodiyo University, Sokoto.

2CollegeOf Medicine and Health Sciences, Federal University Dutse.

3Public Health and Diagnostic Institute, Northwest University Kano, Nigeria.

4Department of Hematology and Blood bank, Rasheed Shekoni Specialist Hospital Dutse.


Alphatocopherol is the main naturally occurring antioxidant substance capable of scavenging free radicals induced by pathological conditions; evidence is accumulating regarding the involvement of oxidative stress among the contraceptive users. The current research consisted of 75 contraceptive users and 42 apparently healthy age-matched controls. Serum levels of alphatocopherol are measured in accordance with method of Neil and Pearson (1907). Statistically (p<0.005) significant higher levels of alphatocopherol was observed among the contraceptive users compared to the control groups, No statistical difference was detected in  different age groups. Alphatocopherol and other antioxidant supplementation should be encouraged among contraceptive users to alleviate oxidative stress.


Key words: Alphatocopherol, Contraceptives, Oxidative Stress, Free radicals.

Post-review Rundown

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