Greener Journal of Medical Sciences

Greener Journal of  Medical Sciences Vol. 8 (1), pp. 001-005, January 2018.

 ISSN: 2276-7797 

Research Article

Manuscript Number: 010618001

(DOI: http://doi.org/10.15580/GJMS.2018.1.010618001)

 

Study on the Effect of Aqueous Extract of Pterocarpussoyauxii (Oha) on Some Haematological and Haemostatic Mechanism of Male Albino Wister Rats

 

 

Oguwike F.N.*, Nwafia W.C, Etoniru I.S, Oguwike E.R.C

 

 

¹ Dept. of Physiology, Faculty of Basic Medical Sciences, Chukwuemeka Odumegwu Ojukwu University Uli Campus Anambra State.

² Dept. of Anatomy, Faculty of Basic Medical Sciences Chukwuemeka Odumegwu Ojukwu University Uli Campus Anambra State.

³ Dept. of Medicine and Surgery, College of Medicine, Chukwuemeka Odumegwu Ojukwu University Uli Campus Anambra State.

Abstract

The study on the haemostatic and haematological effect of leaf aqueous extracts of pterocarpus soyauxii (Oha vegetable) was investigated.

Sixteen (16) albino wistar rats weighing 200-250g were divided into two (2) groups. Group 1 (8 rats) served as control group while Group 2 (8 rats) were the test rats. The control groups were given normal rat pellets and table water while the test groups were given 1.0ml of the extracts for 30 days.

At the end of the feeding for 30 days, blood samples were collected from the animals by cardiac puncture for haematological analysis while cuts were made on their hairless tail for bleeding and clotting times.

Results from the analysis showed a marked decrease (P<0.05) of haemoglobin concentration, packed cell volume, and platelet counts. The bleeding and clotting times, Prothrombin and Partial thromboplastin time kaolin were prolonged in the test animals. It could be concluded that the consumption of P.soyauxii vegetable has an adverse effect on the haemostatic and haematological indices of albino wistar rats

Keywords: Haemostasis, Platelet, Pteridocarpussoyauxii, haemoglobin, white blood cell, coagulation, and clotting time

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