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Oguwike et al

Greener Journal of Medical Sciences

Vol. 10(1), pp. 16-19, 2020

ISSN: 2276-7797

Copyright ©2020, the copyright of this article is retained by the author(s)






Evaluation of Incidence of Mycobacterium Infection and its Effect in the Haematological Values and Lung Volumes of Subjects in Uburu Ohaozara Local Government Area of Ebonyi State



Oguwike F.N1; Nwobodo H.A2; Emenuga V.N3; Offor C.C4; Imanyikwa O.E.I6; Ebede S.O5



1.   Department of Physiology, Faculty of Basic Medical Sciences, Chukwuemeka Odumegwu Ojukwu University Uli Campus, Anambra State

2.   Department Of Medical Laboratory Sciences, Enugu State University Teaching Hospital Enugu Nigeria.

3.   Department of Medical Laboratory Sciences, Faculty of Health Sciences And Technology, University of Nigeria Enugu Campus, Enugu State.

4.   Department of Medical Biochemistry, Faculty Of Basic Medical Sciences, Chukwuemeka Odumegwu Ojukwu University, Uli Campus, Anambra State.

5.    Department of Medical Microbiology, University Of Nigeria Teaching Hospital Ituku Ozalla, Enugu State.

6.    Department of Medical Microbiology, College of Medicine. Enugu State University Teaching Hospital, Enugu Nigeria.






Article No.: 021620035

Type: Research



Mycobacterium are widely distributed throughout the world, and only a few species are pathogenic to man and other mammals, birds, reptiles, and fish (Cruikshank, 1976). Evaluation of mycobacterium infection and its effect on some haematological values and lung volumes in the subjects was studied using those infected with the pathogenic species (Mycobacterium tuberculosis).

Six (6) months intensive research was carried out by screening 150 subjects at Uburu in Ohaozara local government area of Ebonyi state, to study the effect in the haematological values and Lung volumes and its incidence in that region. 32 infected subjects (F: 20 and M: 12) out of the 150 screened between the age range of 17-60 yrs used for the study which was carried out from July –November 2019.

The result of evaluation of incidence shows that the rate of infection of subjects is average (medium). The occurrence in male subjects (40%) than in their female counterparts (60%). Also the infection was noticed to be occurring most in the age range of 18-50yrs. The haematological values especially the erythrocyte sedimentation rate was very high (120 + 0.8 mm/hr westergreen) in both male and female, the haemoglobin (g/dl), PCV (l/l), and the white blood cell differentials were significantly reduced. The high rate of infection of subjects could be due to poor living and feeding condition in the area.


Accepted:  18/02/2020

Published: 22/05/2020


*Corresponding Author

Prof. Oguwike FN

E-mail: foguwike@

Phone: 08037791363



Mycobacterium; Evaluation; Haemoglobin; Lymphocyte; Poor living; Infection








Balcells M.E, Sare T.L, Peter G.F and Alison D.G (2006). Isoniazid Preventive Therapy and Risk for Resistant Tuberculosis. Emerg. Infect. Dis. 12:744-751.


Baker F.J, Silverton R.E, Pallister C.J (1998). Routine Bacteriological Examination of Specimens. Introduction to Medical Laboratory Technology 7th Edition Pg304. Butterworth Heinemann Publishers Linacre House, Jordan Hill, Oxford OX2 8DP.225 Wild wood Avenue, Woburn MA 01801-2041.


Baker F.J, Silverton R.E, Pallister C.J (1998). Erythrocyte sedimentation rate. Introduction to Medical Laboratory Technology 7th Edition Pg374. Butterworth-Heinemann Publishers Linacre Jordan Hill Oxford.


Medical Physiology 11th Edition. Saunders Publishers, 1600 John F. Kennedy Blvd, Suite 1800 Philadelphia, Pg 475.


Chen L.T and Chang P.E (1998). Intrasplenic Induced anaemic rats. Am .J. haematal 11: 403-401


Constable B.J (1963). Changes in blood volume and Prothrombin Time of rats and Guinea pigs from birth to maturity. J. Physiology London. Vol. 197:229-233.


Cruickshank R, Duguid R, Mamoin D.P, Swain A (1976). Mycobacterium tuberculosis’ Medical Microbiology. Published by Churchill Living stone, Medical Division of Longman group LTD, 23 Ravelston Terrace Edinburgh EH4 3TL (Pg 285).


Cruikshank R, Duguid J.P, Mamion B.P, Swain R.S.A (1973). Tuberculin Test. Medical Microbiology 12th Edition, vol.1. churchill Livingstone Publication, 23 Ravelston Terrace, Edinburgh, EH4 3TL (Pg 285)


Koehler C.S.W (2002). Consumption the great killer: Modern Discovery (Vol. 5, No. 2 pp 47-49).


Kolappa C. And Goppi P.G (2002). Tobacco smoking and pulmonary tuberculosis. Thorax 57:964-966. 


Oyebola .D (2002). Pulmonary volumes and capacities. Essential physiology vol.1 Pg99 published by NIHORT Press; ISBN 978-3211-8-6. No.1 NNPC Junction, Abeokuta Rd, Ibadan.


Madigan M.T and Martinko J.M, 2006. Epidemiology of Tuberculosis. Brock Biology of Microorganisms 11th Edition, Pearson Benjamin Cummings Publication USA. ISBN: 0-13-196893-9.


National Institute of Allergy and Infectious Diseases. U.S. Department of Health and Human Services, National Institutes of Health. Tuberculosis. Accessed Dec. 10, 2013.



Cite this Article: Oguwike FN; Nwobodo HA; Emenuga VN; Offor CC; Imanyikwa OEI; Ebede SO (2020). Evaluation of Incidence of Mycobacterium Infection and its Effect in the Haematological Values and Lung Volumes of Subjects in Uburu Ohaozara Local Government Area of Ebonyi State. Greener Journal of Medical Sciences, 10(1): 16-19.


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