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Oguwike et al

Greener Journal of Medical Sciences

Vol. 11(1), pp. 1-7, 2021

ISSN 2276-7797

Copyright ©2021, the copyright of this article is retained by the author(s)

https://gjournals.org/GJMS

 

 

 

 

 

 

Potentiality of Combined Aqueous Extracts of Ginger, Garlic and Lemon Juice in Controlling Obesity and Diabetes Mellitus in Albino Wistar Rats

 

 

Oguwike F.N1, Offor C.C2, Igwedibia C.P1, Ifedi I1, Usige E3, Okeke J1.

 

· Department of Human Physiology, Faculty of Basic Medical Sciences, Chukwuemeka Odumegwu Ojukwu University, Uli Campus, Anambra State.

· Department of Medical Biochemistry, Faculty of Basic Medical Sciences, Chukwuemeka Odumegwu Ojukwu University, Uli Campus, Anambra State.

· Department of Human Anatomy, Faculty of Basic Medical Sciences, Chukwuemeka Odumegwu Ojukwu University, Uli Campus, Anambra State.  


 

ARTICLE INFO

ABSTRACT

 

Article No.: 010421003

Type: Research

 

 

Obesity and diabetes mellitus have been a great challenge to the rich and poor in our society, hence the potentials of combined aqueous extracts of garlic ginger and lemon juice research were embarked upon. Sixty (60) male albino wistar rats weighing 200-250g were selected for this study and they were divided into four (4) groups namely: Group A (15) is the control rats; Group B (15) is the obese rats without diabetes mellitus; Group C (15) is the diabetic rats with no obesity; Group D (15) is the group with obesity and diabetes. All the four (4) groups have their weight measured and they received 1.0ml of the combined aqueous extracts each day for 28 days except the control group that received only feed and water ad libitum. All the rat groups received water also.

Blood samples were collected from the animals after 28 days of acute study and analysis were carried out.  Results of the study showed that the combined extracts of garlic, ginger and lemon juice have the potential elements that reduced glucose in diabetic rats in group C and in group D Table 2 (P<0.05). The diabetic rats in group C and in group D with FBS 160.41 ± 12.4mg/dl and RBS 180.33 ± 0.51mg/dl after days of extracts administration had their sugar level reduced to 93.52 ± 1.46mg/dl and 113.42 ± 0.15mg/dl respectively (P<0.05).             

The obese rats in group B and D had their protein and cholesterol level also drastically reduced (P<0.05) after 30 days extract administration. The rats in group B with their cholesterol 67.1±2.06mg/dl and protein concentration of 2.25±0.4g/dl had their concentration of cholesterol reduced to 40.2±1.51mg/dl and protein 0.08±0.05mg/dl. It could be the presence of the potential and active elements present in the combined extracts that affected the reduction of protein, cholesterol and sugar levels in the test rats. It could be deduced that the combined extracts of garlic ginger and lemon contains active elements that can affect glucose, protein and cholesterol levels in the blood.

 

Accepted:  08/01/2021

Published: 21/01/2021

 

*Corresponding Author

Prof. F.N Oguwike

E-mail: foguwike@ gmail.com

Phone: 08037791363

 

Keywords:

obesity; diabetes; garlic; lemon; ginger; cholesterol; weight; glucose.

 

 


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Cite this Article: Oguwike FN; Offor CC; Igwedibia CP; Ifedi I; Usige E; Okeke J (2021). Potentiality of Combined Aqueous Extracts of Ginger, Garlic and Lemon Juice in Controlling Obesity and Diabetes Mellitus in Albino Wistar Rats. Greener Journal of Medical Sciences, 11(1): 1-7.

 

 

        


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