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Zabbey et al

Greener Journal of Medical Sciences

Vol. 11(2), pp. 249-256, 2021

ISSN: 2276-7797

Copyright ©2021, the copyright of this article is retained by the author(s)







Evaluation of the Hydroethanolic Fruit Extract of Solanum aethiopicum (Garden Egg) on the Concentration of Reproductive Hormones, Sperm Parameters and Histology of the Testis of Male Wistar Rats.



Zabbey VZ; Adienbo OM; Ojeka SO; Dapper DV



Department of Human Physiology, Faculty of Basic Medical Sciences, College of Health Science, University of Port Harcourt, Rivers State, Nigeria.



E-mail: zabbeyvictor@ gmail. com (+2348038786260) ; ologhaguo.adienbo@ gmail. com (+2348030953240); sunday.ojeka@ uniport. (+2348033854898); victor.dapper@ uniport.  (+2348036776322)






Article No.: 120321146

Type: Research

Full Text: HTML, PHP, EPUB


Background: Solanum aethiopicum (eggplant) can either be eaten fresh or cooked and has a long history of consumption in West Africa. This study aimed at evaluating the effects of the hydroethanolic fruit extract of Solanum aethiopicum on serum reproductive hormones, sperm parameters and histology of the testis of male Wistar rats.  

Methods: Thirty-two (32) adult male rats with average weight of 250g were used for the study. The rats were divided into four groups of 8 rats each. Group 1 served as control and was given distilled water only while the experimental groups (groups 2, 3 and 4) were given 100mg/kg, 200mg/kg and 300mg/kg respectively of Solanum aethiopicum fruit extract for 30 days, after which five of the experimental animals in each of the groups were sacrificed.

Results: The results showed a dose-dependent significant increase in the concentration of all the reproductive hormones in the test groups and a significant increase in the percentage sperm motility and viable sperm cells with respect to the control. The testis in the extract treated groups showed no tissue damage when compared with the control.  

Conclusions: Solanum aethiopicum fruit can therefore boost the production of reproductive hormones, improve sperm parameters and preserve the histology of the testis in male Wistar rats.


Accepted:  06/12/2021

Published: 17/12/2021


*Corresponding Author

Zabbey VZ

E-mail: zabbeyvictor@

Phone: +2348038786260



Sperm, Solanum, Hormones, Reproductive, Fruit and Extract.




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Cite this Article: Zabbey VZ; Adienbo OM; Ojeka SO; Dapper DV (2021). Evaluation of the Hydroethanolic Fruit Extract of Solanum aethiopicum (Garden Egg) on the Concentration of Reproductive Hormones, Sperm Parameters and Histology of the Testis of Male Wistar Rats. Greener Journal of Medical Sciences, 11(2): 249-256.


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